Dibchek-GP Tablet

COMPOSITION:

EACH FILM COATED TABLET CONTAINS:

PRESENTATION:
Dibchek-GP Tablets are available in the pack of 10×10 tablets.

INDICATIONS:
Non-insulin dependent diabetes mellitus, diabetes with or without obesity in adults.

DESCRIPTION:
Dibchek-GP Tablet is a combination of Glipizide and Metformin Hydrochloride. Glipizide is a sulphonylurea which reduces blood glucose level by stimulating the release of insulin from pancreatic cells. Metformin is a biguanide which improves hepatic and peripheral tissue sensitivity to insulin hence improves glucose tolerance in patients with Type II diabetes. It reduces the amount of glucose produced by liver and absorbed by small intestine.

CONTRAINDICATIONS:
Dibchek-GP Tablet is contraindicated in patients with known hypersensitivity to any of the ingredients of the product and in conditions such as insulin-dependent diabetes mellitus, renal or hepatic failure, alcoholism, patients undergoing surgery, cardiac failure, pregnancy and lactation.

SIDE EFFECTS:
Hypoglycaemia, skin eruption, nausea, vomiting, diarrhoea, metallic taste in mouth may occur occasionally. Symptoms of side effects (if any) should subside after discontinuing medicine. If symptoms persist, please consult doctor.

DOSAGE:
Adult: Take with meals. First-line: initially 2.5mg/250mg once daily; or, if fasting plasma glucose is 280–320mg/dL, may start at 2.5mg/500mg twice daily. May increase by 1 tab/day every 2 weeks; max 10mg/1000mg or 10mg/2000mg per day in divided doses. Second-line: (previously treated with sulfonylurea or metformin only): 2.5mg/500mg or 5mg/500mg twice daily (AM & PM) (initial dose should not exceed previous daily doses of individual components); may increase by increments of ≤5mg/500mg up to minimum effective dose or max 20mg/2000mg per day. Previously treated with combination therapy (sulfonylurea plus metformin): may be switched to 2.5mg/500mg or 5mg/500mg (initial dose should not exceed previous daily doses of individual components). Elderly: avoid max doses.
Children: Not established.

STORAGE:
Store in a dry place below 25°C/ 30°C. Keep out of the reach of children.